§ amoxicillin and clavulanate potassium 250 mg/125 mg tablet is NOT substitutable with amoxicillin and clavulanate potassium 250 mg/62.5 mg chewable tablet. ‡ Two amoxicillin and clavulanate potassium 250 mg/125 mg tablets are NOT substitutable with one 500 mg/125 mg amoxicillin and clavulanate potassium tablet. † Adults who have difficulty swallowing may be given the amoxicillin and clavulanate potassium 125 mg/31.25 mg per 5 mL or amoxicillin and clavulanate potassium 250 mg/62.5 mg per 5 mL suspension in place of the 500 mg/125 mg tablet. * Adults who have difficulty swallowing may be given the amoxicillin and clavulanate potassium 200 mg/28.5 mg per 5 mL suspension or the amoxicillin and clavulanate potassium 400 mg/57 mg per 5 mL suspension may be used in place of the 875 mg/125 mg tablet. One 250 mg tablet § of amoxicillin and clavulanate potassium every 8 hours One 500 mg tablet †, ‡ of amoxicillin and clavulanate potassium every 12 hours One 500 mg tablet †, ‡ of amoxicillin and clavulanate potassium every 8 hours One 875 mg tablet* of amoxicillin and clavulanate potassium every 12 hours Severe infections and infections of the respiratory tract In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.ĭOSING REGIMEN OF AMOXICILLIN AND CLAVULANATE POTASSIUM When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. To reduce the development of drug-resistant bacteria and maintain the effectiveness of amoxicillin and clavulanate potassium and other antibacterial drugs, amoxicillin and clavulanate potassium should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When susceptibility test results show susceptibility to amoxicillin, indicating no beta-lactamase production, amoxicillin and clavulanate potassium should not be used. coli, Klebsiella species, and Enterobacter species. Urinary Tract Infections - caused by beta‑lactamase‑producing isolates of E.
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